Exploring Pharmaceutical Treatments for PE

Other > premature ejaculation medicine


For men, erectile dysfunction and ejaculatory problems are the most common sexual difficulties. With the introduction of Viagra however, problems of erectile dysfunction are much less frequent and more easily treated.

  • Dapoxetine is specifically designed for on-demand use in PE.
  • Topical anesthetics require minimal use to avoid excessive numbness.
  • SSRIs impact neurotransmitters involved in ejaculation control.
  • Tramadol's side effects limit its routine use for PE.
  • Non-drug approaches include psychological counseling and exercises.
  • Pelvic strengthening exercises aid in delay of ejaculation.
  • Partner education enhances understanding and support.
  • Managing stress and anxiety can significantly improve PE.
  • Some therapies combine medication with sex therapy sessions.
  • Medical evaluation is essential before initiating treatment.
  • Lifestyle factors like smoking can influence sexual performance.
  • Patient adherence to treatment plans improves outcomes.

In contrast, ejaculatory problems continue to be commonplace among men and often create feelings of shame and embarrassment for those men who struggle with this difficulty. When does an ejaculation problem become a disorder? This is a subjective question and is based on the level of distress that is experienced by the man or his partner. The time from initiating sexual activity to ejaculation varies from one individual to another. This time period is called the ejaculatory latency. What may be a problem for one man may be acceptable to another.

Does Viagra help premature ejaculation?

No office wait times or scheduling issues typical with physical medical practices. Start your PE treatment today with our quick and easy online assessment. Please be advised there are two sections on this topic, one by Dr. Stanley Ducharme, a sex therapist, and one by Dr. Ricardo Munarriz, a sexual medicine physician. Typically, ejaculatory disorders fall into two categories. These are: delayed ejaculation and early ejaculation. This column will explore some of the psychological factors and treatment options related to these two distinct male dysfunctions. In the vast majority of cases, the most effective therapeutic approach for ejaculatory dysfunction is a combination of biologic and psychologic therapy. In this way, both the emotional and physical aspects of the problem can be addressed. From an emotional standpoint, it is important to understand the history and background of the individual. Issues such as depression, anxiety, past sexual experiences, psychological trauma and relationship history are important considerations that need to be discussed early in the evaluation.

Product Dosage Quantity + Bonus Price
Kamagra Polo100mg272 + 12 Pills622.94€ 593.28€
Viagra Generic100mg30 + 4 Pills60.91€ 58.01€
Kamagra Gold50 mg180 + 6 Pills371.27€ 353.59€
Cialis Generic10mg20 Pills48.23€ 45.93€
Cialis Original20mg64 + 4 Pills274.18€ 261.12€
Tadalista Super Active20mg30 + 6 Pills128.09€ 121.99€
Cialis Generic2.5mg360 + 10 Pills260.03€ 247.65€
Cialis Original20mg4 Pills41.99€ 39.99€
Kamagra100mg32 Pills121.24€ 115.47€
Viagra Generic50mg90 + 6 Pills107.37€ 102.26€
Cialis Professional20mg10 Pills48.29€ 45.99€

Regardless of the psychological issues, a good medical or urologic work-up is always encouraged before embarking on a behavioral treatment program.

Analgesic, Opioid

Retail price for sildenafil can be upward of $45 per dose.14 With RedBox Rx, sildenafil starts as low as $1 per dose. Tadalafil (generic Cialis) is also commonly prescribed for erectile dysfunction. Tadalafil can help treat PE, especially if symptoms for PE and ED are both present. Studies show that taking tadalafil for PE can help men last longer before finishing.15 A prescription is required to purchase tadalafil for PE – with the cost per tablet (without insurance) averaging around $12 per tablet.16 Tadalafil is available for as low as $1 per dose with RedBox Rx. Vardenafil (generic Levitra) is commonly prescribed for ED and has shown promise as a PE treatment as well.

Sildenafil (Viagra)

In studies, men improved their lasting time, recovery period, control and satisfaction during sexual activity.17 A prescription is required for vardenafil, and without insurance it can cost more than $50 per tablet.18 Vardenafil starts at $3 per tablet with RedBox Rx. RedBox Rx makes receiving treatment for premature ejaculation easy and affordable. Transparent, affordable, flat rates for PE medications with SSRIs for $25 per month (with purchase of three-month supply). $25 online consultations with a U.S. licensed medical professional. In this manner, any medical considerations that contribute to the problem can to be understood from the onset. From a libido gummies female uk medical perspective, ejaculatory dysfunction is often considered to be a nerve related issue.

Drug Name Approval Year Primary Use Recommended Dosage Prescription Needed Monitor Required Typical Side Effects
Dapoxetine 2009 Premature ejaculation 30 mg before sex Yes Yes Nausea, dizziness
Paroxetine Approved for other uses, off-label for PE 20 mg/day Yes Yes Yes Fatigue, sexual dysfunction
Sertraline Approved for depression, off-label for PE 50 mg/day Yes Yes Yes Insomnia, digestive issues

In such cases, penile sensitivity may be evaluated using various instruments that produce vibration. In addition, a medical history is obtained paying particular attention to any previous neurologic injury or trauma to the penis. Other sexual dysfunctions such as low desire and erectile dysfunction may also accompany the ejaculatory problem and need to be addressed. The psychological definition of delayed ejaculation refers to the inability to have an ejaculation during sexual intercourse.

  • Dapoxetine has a rapid onset, typically within 1-3 hours.
  • Topical anesthetics should be applied in small amounts to avoid overdose.
  • SSRI side effects may include sleep disturbances or gastrointestinal upset.
  • Tramadol can cause dizziness, dry mouth, and nausea as side effects.
  • Behavioral techniques teach men to recognize early signs of ejaculation.
  • Pelvic floor training can enhance ejaculatory control.
  • Counseling sessions help address performance anxiety and stress.
  • Medications should be used as prescribed to minimize risks.
  • Some men respond better to combination therapies.
  • Abstaining from excessive masturbation may help in some cases.
  • Lifestyle changes and psychological support are important adjuncts.
  • Any medication or supplement should be discussed with a healthcare professional.

Interestingly enough, ejaculatory issues are rarely defined as a dysfunction if they occur only during masturbation. As a result, an important diagnostic question for sex therapists is the context in which the problem occurs. Does this difficulty occur with self-stimulation, with all partners or with specific partners? This question will ultimately be important as a treatment program is designed and implemented.

Strategy Description Expected Outcome Time Frame Additional Notes
Mindfulness Meditation Practice focusing on the present moment to reduce anxiety Reduced performance anxiety Weeks to months Complements other treatments
Sensate Focus Exercises Partner-based touching exercises to build comfort Increased control and intimacy Several weeks Requires partner cooperation
Cognitive Behavioral Therapy Therapy addressing thoughts and anxiety related to sex Better sexual confidence Several sessions Often part of a comprehensive plan

Problems of delayed ejaculation tend to be somewhat rare and not well understood by psychologists and sex therapists. In addition, they are not well understood by most medical doctors and urologists. It is not unusual for doctors to minimize the dysfunction and to dismiss it. For many men, finding the right professional, who has experience and realizes the seriousness of the problem may be one of the most difficult aspects in the treatment process. In many cases, the man himself may tend to delay treatment or to minimize the distress of the situation.

Additional information

Because of this, medical providers often prescribe SSRIs for PE. Sertraline (generic Zoloft) is part of the classification of drugs called SSRIs. It is used for the treatment of a wide range of conditions, including depression, anxiety, OCD, PTSD and PMS.7 Although it’s not known exactly how it works, studies8 have shown that sertraline does work for PE. The retail price for sertraline (without insurance) is around $37 for a one-month supply.9 At Redbox Rx it starts at $25 per month. Paroxetine (generic Paxil) is another SSRI that has shown promising study results for treating PE.10 Although it is difficult to prove, some researchers believe that SSRIs ability to reduce depression and anxiety could be the foundation for treating PE.

Squeeze technique

PE is a condition that can be wholly psychological rather than fully biological. Paroxetine for PE is available by prescription only and can cost upward of $28 per month without insurance coverage. A RedBox Rx paroxetine prescription starts at $25 per month. All RedBox Rx PE prescription medication options are buy vardenafil 40mg FDA-approved, competitively priced, and customized to your health needs by a licensed U.S. medical professional.

Early Climaxing Before or Shortly after Penetration

PDE5 inhibitors are a classification of medications traditionally prescribed for erectile dysfunction. Additionally, research has shown that PDE5 inhibitors can have positive results when prescribed for premature ejaculation. The best result for treating premature ejaculation is a combination of a PDE5 inhibitor and an SSRI, according to research.11 Sildenafil (generic Viagra) is a commonly prescribed medication to treat erectile dysfunction. Studies12 have shown that sildenafil also benefits men that experience PE. In addition to helping delay ejaculation during vaginal intercourse, study participants reported an increase in sexual confidence, satisfaction and a decrease in recovery time to achieve a second erection after ejaculation.13 A prescription is required to purchase sildenafil for PE. At other times, there is the hope that ejaculatory problems will disappear without proper treatment. Unfortunately however, problems such as delayed ejaculation seldom disappear without professional intervention. For many men, feelings of shame prevent them from seeking medical and professional help. In spite of the lack of information regarding delayed ejaculation, the most successful approach, for sex therapists, is to engage both members of the couple into addressing the problem.

Ethics declarations

Oral medications can help men maintain an erection or delay climax. Two main categories used for premature ejaculation are selective serotonin reuptake inhibitors (SSRIs), which are a type of antidepressant, and PDE5 inhibitors, which are typically prescribed for erectile dysfunction. Topical treatments are applied directly to the genitals anywhere from five to 20 minutes before intercourse to reduce sensation and have been shown to delay orgasm in men by three to six minutes.2 However, for some users, topical treatments can cause loss of sexual desire or erectile disruption due to numbness.3 One risk of using topical treatments for PE is that the numbing ingredients can transfer to your partner, reducing sensation for them as well. Using a condom can mitigate the transfer of topical treatment to your partner during sexual contact. Lidocaine cream is a topical PE medication that numbs the application area with local anesthetics.

Tadalafil (Cialis)

When applied to male genitals, desensitization helps prolong an erection and prevent premature ejaculation. Lidocaine is available via a prescription or over the counter. RedBox Rx offers prescription-strength 4% lidocaine cream in a 15 gm tube for $30. Benzocaine is a mild anesthetic that is widely available in over-the-counter pain relief products. When used topically on the skin, it can create numbness and desensitizes the area.

What to expect from your doctor

Benzocaine wipes4 have been developed specifically for PE as a convenient method to apply anesthetic to the genitals. Its ability to help men with PE last longer during intercourse has shown promise in small studies. Benzocaine wipes for PE are available over the counter. The price for benzocaine wipes varies widely – averaging approximately $2 to $6 per wipe.5 Selective serotonin reuptake inhibitors (SSRIs) are medications generally prescribed for mental health conditions like depression and anxiety. One of the side effects of SSRIs is delayed ejaculation and studies6 show this can help with PE symptoms. Thus, ejaculatory dysfunction is always perceived as a couple’s issue. Resolving the problem is most successful when both partners can work together as a team toward a successful solution.

  • Dapoxetine is effective when taken 1-3 hours before intercourse.
  • Topical anesthetics can reduce sensation but risk partner numbness.
  • SSRIs may take several weeks to reach full efficacy for PE.
  • Tramadol's use for PE is off-label; consult a doctor before use.
  • Combining medication with therapy can optimize outcomes.
  • Avoiding excessive alcohol and stress can improve sexual performance.
  • Pelvic exercises increase muscle strength and ejaculatory control.
  • Psychological support can address anxiety-related PE.
  • Devices like constriction rings may be used as mechanical aids.
  • Open communication with partner improves treatment success.
  • Regular follow-up with healthcare provider is recommended.
  • Natural remedies lack solid clinical proof but are popular.

If the man is in a relationship, he needs the support and understanding of his partner. This helps to insure a successful treatment.

Side Effect Medication Type Incidence Rate Severity Level Management Strategies Notes
Nausea SSRIs, topical anesthetics 10-15% Mild to Moderate Dose adjustment, timing Usually transient
Dizziness SSRIs, topical anesthetics 8-12% Mild Standing slowly, hydration Common with beginning treatment
Headache SSRIs, topical anesthetics 5-10% Mild Analgesics, time to adjust Typically diminishes over time
Reduced Sensation Topical anesthetics 10-20% Mild Reduced dose, application timing Can affect partner satisfaction

Otherwise, the partner’s frustration and distress may contribute to the continuation of the problem. Overcoming an ejaculation problem when under stress and pressure from a partner is extremely difficult for any man. Ejaculatory problems can have a devastating affect on self-esteem. Men with ejaculation problems undoubtedly have feelings of inadequacy, feelings of failure and a negative view of themselves.

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