Medical Conditions That Affect Female Sex Drive

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In this review, there were four articles on Russian olive, two on chaste tree, two on bindii, two on ginseng, one on carrot seed, one on fenugreek, one on saffron, one on rose flower, one

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Sexual dysfunction can have devastating effects on women’s self-respect, a sense of being total and complete, and interactive relationships while also contributing to mental disorders. FSD can cause conflicts and ultimately lead to divorce or negative effects on fertility (6). Women's sexual life and fertility are strongly affected by their sexual disorders, while various biological, psychological, and social factors contribute to the prevalence of sexual disorders. Persistently notable risk factors for sexual dysfunction include disability, mental disorders, tension, miscarriage, urogenital problems, female genital mutilation, miserable relationship, and sexual harassment and rape (7). Many treatments, including chemical drugs, have been investigated to improve FSD.

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However, complementary medicine has been proposed as an appropriate alternative for improving sexual function disorders due to concerns about the side effects of chemical drugs (8). Hence, many affected individuals often seek alternative treatments, such as herbal medicines, despite developing new drug therapies for sexual dysfunction (3). The mechanism of action of these medicines is not fully known; however, according to recent research, the medicinal substances in these herbs can enhance sexual function by affecting the brain, endocrine system, and gonads. Herbal medicines also have antioxidant and anti-inflammatory properties that may improve sexual function (9). However, there is no effective herbal or even chemical treatment approved by the US Food and Drug Administration (FDA) for FSD so far, or the therapeutic effects have been limited to placebo and trial and error.

IN CLINICAL TRIALS1, WOMEN ON ADDYI EXPERIENCED:

Accordingly, new studies continue to prove the medical efficacy of herbs cenforce tablets and find effective herbal remedies (10). If the effects of herbal medicines on the improvement of female sexual function and sexual satisfaction are investigated and confirmed, these medicines can replace chemical medicines. Therefore, considering the high outbreak of FSD among women of reproductive age and the tendency of the affected individuals to use complementary medicine, this systematic review aims to investigate the effects of herbal medicines on sexual function and sexual satisfaction of women of reproductive age. The research population of the current systematic review included all randomized clinical trial studies on the effects of herbal medicines on sexual function and sexual satisfaction of women of reproductive age. The researchers searched the international databases of Google Scholar, Web of Science, Scopus, Science Direct, PubMed, Cochrane Library, and the national SID database. on palm pollen, one on celery seed, one on winter cherry, one on lemon balm, one on pomegranate peel, one on squill bulb, and one on a mixture of oak gall, pomegranate peel, and fenugreek seed.

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All studies used a placebo control group except for one study in which the control group received no medication.

Key takeaways:

Finally, 21 articles with a total sample size of 1625 were evaluated after the removal of duplicate articles by a review of the titles, abstracts, and then the full texts (Figure 1). Two studies were excluded due to lack of access to the full text, and one study was excluded due to re-reporting results in a new study. All articles were randomized controlled clinical trials published during 2014 - 2022. Among the included studies, only one had a cross-sectional, and others followed a parallel design. Most of the studies were conducted in Iran (17 studies), two in America, and in Bulgaria, Brazil, Australia, India, and South Korea, one study each. All studies used the female sexual function index (FSFI) (Table 1).

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A summary of the studies included in the systematic review and the herbs used in the studies is provided in the following.

How does it work?

Jones: Right, and I usually recommend taking some time out for each other. I ask them, what kind of pattern of intimacy do you have when you and your partner go on vacation? "Oh yeah, when we're away we have great hotel sex." Well, there are no kids around, there are no dishes, and definitely no bills, you're in a brand new bed, it's a new place. But if women say, "I don't want to do all that thing," it's like dieting and exercise, "Just give me a pill doctor so I can lose weight, just give me a pill." What I am afraid of is that I will get calls from husbands, "I want you to fix my wife. I want you to give her that pill." So if this is being driven by the partner, I need to get buy-in by my patient that she's really interested, because she may have some side effects.

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And if she's really not interested in becoming interested, then this is not for her. If she's interested in becoming interested, I think it's worth a try for a couple of weeks. And if she doesn't have significant side effects and it improves her intimate life, just thinking about sex makes people have sex more often, so the placebo effect can be significant. Announcer: TheScopeRadio.com is University of Utah Health Sciences Radio. If you like what you heard, be sure to get our latest content by following us on Facebook.

7. Discussion

Sexual dysfunction refers to dissatisfaction with sexual function leading to distress (1). According to the Diagnostic and Statistical Manual of Mental Disorders (DSM), female sexual dysfunction (FSD) includes sexual desire/arousal, orgasm, and genito-pelvic pain/penetration disorders (2). These disorders root in vascular, nervous, hormonal, or psychological causes (3). Forty-one percent of women of reproductive age worldwide mention sexual dysfunction as a common medical problem (4). There is a powerful link between sexual dysfunction and quality of life, known as a common health problem all over the world (5). Abbreviations: FSFI, female sexual function index; FSDS, Female Sexual Distress Scale; SAR, sexual activity record; BDI, beck depression inventory; DISF-SR, derogatis interview for sexual function-self report; QS-F, Sexual Quotient Female Questionnaire.

3. Ginseng

The instrument consists of eight items to examine the randomization method and latent allocation, similarity of prognostic factors at baseline, specification of eligibility criteria, blinding of evaluators, providers, and participants, presentation of point estimates for outcome measures, and intention-to-treat analysis. For each question, the “Yes/No” and “No Idea” answers were given 1 and 0 points, respectively (11). Articles with a score of ≥ 3 were included in the study. According to the research objectives, this study examined all published articles in electronic databases. A total number of 1120 articles (Google Scholar = 737; Cochrane Library = 37; Web of Science = 23; Scopus = 169; Science Direct = 112; PubMed = 24; SID = 18) were extracted through primary search using relevant keywords. In Sadeghi et al.’s (2020) study, carrot seed improved the total scores of sexual function (7.329 ± 0.830, P < 0.001), desire (4.1 ± 0.7, P < 0.001), moisture (4.7 ± 0.8, P = 0.019), arousal (0.8 ± 4.1, P < 0.001), satisfaction (1.1 ± 4.8, P < 0.001), orgasm (0.9 ± 3.9, P < 0.001), and pain (1 ± 5.4, P = 0.001) (12). According to Dalil Heirati et al.’s (2020) study, there was no statistically important difference between the two groups in terms of the total mean scores of sexual function and its dimensions after one month of intervention (P ≥ 0.05).

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Only the score of orgasm showed an improvement in the comparison of intragroup scores (P = 0.02) (13).

The bottom line

A manual search was also carried out to find the articles that could not be retrieved in the electronic search. This study examined only English or Persian language articles. All relevant articles published from 2000 to February 28, 2022, were reviewed by two independent researchers. The keywords of "sexual function, sexual dysfunction, sexual health, sexual disorders, sexual disorder, sexual satisfaction, herbal medicine, herbal treatment, herb, women, and female" were selected using the MeSH tool to find related articles in the databases, combined with Boolean operators of OR and AND. The search in the mentioned databases resulted in the retrieval of 1120 articles, which were then entered into EndNote software.

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Accordingly, 148 duplicate articles were identified and removed using EndNote software, followed by the examination of the titles and abstracts of 977 articles. Of the remaining articles, 939 were removed because they were not related to the objectives of the present study, after which the full texts of the remaining 38 articles were studied. The corresponding author was contacted and asked to provide the article’s full file when it was not available online. A manual search was also performed in related articles to obtain a bigger sample. Finally, 21 articles were included in the study (Figure 1) after reviewing the inclusion criteria, and their quality was gel erectile dysfunction evaluated by two independent authors using Verhagen’s checklist.

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The inclusion criteria included randomized controlled clinical trial studies published in English or Persian on a sample of women aged 15 - 51 years without depression investigating sexual function or sexual satisfaction in which the control group had received herbal medicines. Papers whose full texts were not available, observational, qualitative, and review studies, article abstracts, and letters to the editor were excluded. A researcher-made form was used to extract data from the texts of the selected articles. The form included details such as the author’s name, publication year, research location, study design, sample size, participants’ age, intervention type, side effects, data collection tools, findings, and results of evaluating the quality of the article. The quality of the articles was evaluated using Verhagen's checklist, designed to measure the quality of randomized clinical trial studies.

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